Personalized embryo transfer (pET) is an approach used in assisted reproductive technology (ART) that involves selecting the most suitable embryo for transfer into the uterus based on individualized criteria. The goal of personalized embryo transfer is to increase the chances of a successful pregnancy by tailoring the embryo selection process to the specific needs and characteristics of the intended parent or couple.

1. In vitro fertilization (IVF):Similar to standard IVF, eggs are retrieved from the female partner’s ovaries and fertilized with sperm in a laboratory setting to create embryos.
2. Embryo culture: The resulting embryos are allowed to develop and grow in a controlled environment for a few days, typically up to the blastocyst stage.
3. Comprehensive embryo assessment: Various methods of embryo assessment are employed to evaluate the quality and developmental potential of each embryo. These assessments may include morphological evaluation (looking at the appearance and structure of the embryo), time-lapse imaging (observing embryo development in real-time), and genetic screening (PGS/PGT-A) to check for chromosomal abnormalities.
4. Personalized criteria: based on individuals window of implantation determined by era test specially in cases of previous ivf failures with good embryos transfer is taken place so that patients have transfer as per their personalised window to increase the chances of success by 20 percent.
5. Selection of the best embryo:Using the personalized criteria, the fertility specialist or embryologist selects the embryo that is deemed most likely to result in a successful pregnancy.
6. Single embryo transfer (SET): In many cases, personalized embryo transfer involves transferring a single embryo into the uterus. This approach helps to reduce the risk of multiple pregnancies while maintaining a good chance of achieving a viable pregnancy.

1. Increased pregnancy success rates: By carefully selecting the embryo that is most likely to result in a successful pregnancy, personalized embryo transfer aims to improve the overall success rates of IVF.
2. Reduced risk of multiple pregnancies: Transferring a single embryo reduces the likelihood of multiple pregnancies, which carry higher risks for both the mother and babies.
3. Customized treatment: The approach takes into account individual factors, allowing for a more tailored and individualized IVF treatment plan.

It’s essential to note that personalized embryo transfer is a highly specialized technique, and its success depends on the expertise of the fertility clinic, embryologists, and reproductive endocrinologists involved in the process. Not all fertility clinics may offer personalized embryo transfer, and its applicability may vary based on the specific circumstances of each patient.